HORMONE REPLACEMENT THERAPY LAWYER

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Types of Common Hormone Replacement Therapy Drugs:

Prempro

Wyeth Pharmaceutical’s Prempro is the number one selling hormone replacement drug that was the source of concern and the reason why the WHI study was halted. The combination of estrogen and progestin in Prempro was intended to help a woman with menopausal symptoms like hot flashes and mood swings. Prempro and Wyeth’s related product Premphase generated more than $2 billion in sales in 2001.

Premarin

Wyeth’s Premarin is an estrogen replacement therapy pill that has been available for sixty years. Estrogen replacement therapy is usually prescribed for women who have had a hysterectomy. The WHI study is still continuing on estrogen only hormone replacement therapy because researchers have not yet determined the risk and benefit of the pills. Last year, Premarin had $1.3 billion in sales.

Premphase

Premphase is a hormone replacement drug similar to the other drug Prempro, combining estrogen and progestin. As with Prempro, Premphase is for women who have not had hysterectomies.

Your Legal Rights
 

Hormone Replacement Therapy Lawyer

If you have received hormone replacement therapy, it is pertinent that you contact a hormone replacement lawyer.

Every day there are about 5,000 American women that reach menopause, the permanent end of menstruation. For decades, women have been using hormone replacement therapy so commonly that it has almost become synonymous with the onset of menopause. Medical experts had been telling doctors to encourage almost every woman to take hormone replacement therapy when reaching menopause, fueling the estrogen-progestin regimen to become one of the most common prescriptions written 70 million times a year and taken by 6 million American women. According to Dr. Issac Schiff, “ten years ago, it was almost malpractice not to endorse estrogen. Now the bubble has burst,” (Time 7/22/02).

On July 9, 2002, information was released from the Women’s Health Initiative (WHI) study involving over 16,000 healthy women after it was halted three years earlier than planned. Researchers concluded it would be unethical to continue the study because of the surprising findings linking hormone replacement therapy to heart disease, breast cancer, stroke, and blood clots. The WHI study was the first and only large study comparing the effects of hormone replacement therapy with placebos in healthy women. Originally believed to prevent heart disease, the study provided answers to the ongoing debate of whether the risks or the benefits or hormone replacement therapy outweighed one another.

Mangement of Symptoms
In a recent survey, doctors reported that management of symptoms is a treatment goal for 9 out of 10 new patient starts with combination hormone replacement therapy

 

Women’s Health Issues Overlooked?
Groups have been opposed to hormone replacement therapy from the start, refusing to believe the claims and questioned the data available on its’ effectiveness. The National Women’s Health Network was astounded when Wyeth, the company that makes the leading hormone replacement therapy pill Prempro, went to the FDA asking for a label change as protective against heart disease. The group’s surprise was the fact that they felt a drug for healthy men would never be approved without a randomized clinical trial.

Lobbying women’s groups in addition to criticism by congresswomen regarding the lack of attention that is paid towards women’s health pushed Congress to appropriate money for the WHI study that was performed at the National Institutes of Health. The results seemed to exhibit exactly why certain groups were never convinced of what hormone replacement therapy claimed it could do. Dr. Fletcher and Dr. Graham of Harvard Medical School found that “the whole purpose of healthy women taking long-term estrogen/progestin therapy is to preserve health and prevent disease. The results of this study provide strong evidence that the opposite is happening for important aspects of women’s health, even in the absolute risk is low.”

Doctors and women alike were shocked and confused at how one of the most common prescriptions that millions of women were taking was just found to do more harm than good. Linked to increases in breast cancer, heart attacks, strokes, and blood clots, women and doctors are trying to figure out the future for menopausal women. For many women, stopping their hormone replacement therapy will not be difficult for the minimal symptoms they experience temporarily, like hot flashes and mood swings, leading many to wonder why if the hormones were so insignificant in their transition to menopause their doctors encouraged them to use the pills. For decades hormone replacement therapy has been used without knowing the long-term risks and side effects associated to the drug.

If you would like to receive more information on hormone replacement drugs including Prempro, Premarin, and Premphase contact us.



Breaking News!! OCTOBER 2003
Ovarian Risk Amongst Combined Hormone Replacement Therapy Users
Women taking estrogen plus progestin were diagnosed as having invasive ovarian cancer at a rate of 42 per 100,000 person-years in comparison to the 15 per 100,000 person-years in the placebo group. The Hormone Replacement Therapy study analyzed trial data collected for the Women’s Health Initiative trial involving 16,608 postmenopausal women who had not had a hysterectomy at enrolment and were using a certain combination of Hormone Replacement Therapy drugs. Read Full Article....

More Hormone Replacement Therapy News....

Hormone Replacement Therapy Side Effects

Over 16,000 women participated in a major clinical trial that was stopped because of the serious risks found to occur when using hormone replacement therapy including:

Heart Disease- The Women’s Health Initiative study showed that estrogen/progestin hormones do not protect against heart disease as earlier thought. The study found that hormone replacement therapy actually raises the risk of heart disease by 23%.

Breast Cancer- The Women’s Health Initiative definitively proved that hormone replacement therapy does raise the risk of invasive breast cancer. The earlier thirty studies was unable to prove this serious risk that was shown to occur 26% more in women taking hormone replacement therapy pills.

Stroke- Strokes become more likely as people age and as their blood vessels age as well. When blood vessels age they become less flexible and can lead to buildup in blood pressure that causes strokes. Women taking hormone replacement therapy are at higher risk of blood clots because estrogen tends to promote them. The blood clots can add to the risk of stroke that was found to occur 38% more in women on hormone replacement therapy.

Blood Clots- Blood clots have been shown to occur 100% more in women taking hormone replacement therapy. The high increased risk of blood clots also raises the risk of stroke.

Who Does the WHI Study Affect?
There were an estimated 38% of women past menopause taking hormone replacement therapy when the announcement of the study’s data was released, with around 70 million prescriptions written every year. In one year’s time, for every 10,000 women who take estrogen-progestin combination, there will be eight more breast cancers, eight more strokes, and seven more heart attacks. Due to the millions of women that take the hormone replacement therapy the number of illnesses quickly add up.

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Not certified by the Texas Board of Legal Specialization.

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